Cayenne, as a spice, always refers to the powdered form of this hot pepper. This medium-heat pepper is widely used in cuisines from around the world. Many people use a pinch of cayenne to spice up their cornbread, stir fry, hamburgers, meatloaf and salads. A bit in ranch dressing can create a new taste that's fantastic. Let your imagination run free and use it in any recipe where you want a little (or a lot) more heat.